Resveratrol-associated renal toxicity. Nicolini, G., Rigolio, R., Miloso, M., Bertelli, A. 10-15-2001;61(20):7456-7463. Nutr.Res 2011;31(11):842-847. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. View abstract. Fujitaka, K., Otani, H., Jo, F., Jo, H., Nomura, E., Iwasaki, M., Nishikawa, M., Iwasaka, T., and Das, D. K. Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment. Abou-Zeid LA, El-Mowafy AM. View abstract. Timmers, S., Konings, E., Bilet, L., Houtkooper, R. H., van de Weijer, T., Goossens, G. H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S., Moonen-Kornips, E., Hesselink, M. K., Kunz, I., Schrauwen-Hinderling, V. B., Blaak, E. E., Auwerx, J., and Schrauwen, P. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. J Neuroophthalmol. 2001;8(6):408-419. 3,5,4' TriHydroxy-Transstibene, (E)- 5-(4-hydroxystyryl)benzene-1,3-diol, 3,4',5-stilbenetriol, 3,5,4' -trihydroxystilbene, 3,4',5-trihydroxystilbene, 3,5,4'-trihydroxy-trans-stilbene, Cis-Resveratrol, Extrait de Vin, Extrait de Vin Rouge, Kojo-Kon, Phytoalexin, Phytoalexine, Phytoestrogen, Phyto-œstrogne, Pilule de Vin, Protykin, Red Wine Extract, Resvratrol, Resveratrols, Resvratrols, RSV, RSVL, Stilbene Phytoalexin, Trans-Resveratrol, Trans-Resvratrol, Wine Extract, Wine Pill. J.Pharmacol.Exp.Ther. Some medications changed by the liver include amitriptyline (Elavil), carisoprodol (Soma), citalopram (Celexa), diazepam (Valium), lansoprazole (Prevacid), omeprazole (Prilosec), phenytoin (Dilantin), warfarin, and many others. Bhavnani, B. R., Cecutti, A., Gerulath, A., Woolever, A. C., and Berco, M. Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women. 2005;135(8):1911-1917. Effect of resveratrol on alcohol-induced mortality and liver lesions in mice. Am J Cardiol. J Nutr 2004;134:5-10. View abstract. View abstract. Holian, O., Wahid, S., Atten, M. J., and Attar, B. M. Inhibition of gastric cancer cell proliferation by resveratrol: role of nitric oxide. View abstract. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. Klinge, C. M., Risinger, K. E., Watts, M. B., Beck, V., Eder, R., and Jungbauer, A. Estrogenic activity in white and red wine extracts. 2000;78(11):874-881. Antiviral Res. 2010;19(4):1359-1370. 2014 Dec;12(10):497-501. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. Cancer Res 2004;64:1452-9. vitamins, herbs, dietary supplements a-z list. View abstract. when used in the amounts found in foods. View abstract. Oncol Rep 2004;11:441-6. Pancreas 2009;38(8):947-953. Oat consumption does not affect resting casual and ambulatory 24-h arterial blood pressure in men with high-normal blood pressure to stage I hypertension. View abstract. View abstract. 11-21-2001;70(1):81-96. View abstract. 8-15-2001;61(16):6137-6144. View abstract. Resveratrol is POSSIBLY SAFE Nat Rev Drug Discov. Am J Clin Nutr. Differential recognition of resveratrol isomers by the human estrogen receptor-alpha: molecular dynamics evidence for stereoselective ligand binding. J Alzheimers.Dis. Endocrinology 2000;141:3657-67. Int.J Clin.Pharmacol.Ther 2008;46(11):564-570. 2011;106(3):383-389. Life Sci 11-10-2000;67(25):3103-3112. View abstract. View abstract. Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling. View abstract. Bass, T. M., Weinkove, D., Houthoofd, K., Gems, D., and Partridge, L. Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans. Cancer Res 10-1-2010;70(19):7392-7399. Antiplatelet activity of synthetic and natural resveratrol in red wine. View abstract. Dudley, J. I., Lekli, I., Mukherjee, S., Das, M., Bertelli, A. View abstract. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. Medicine & Science in Sports & Exercise 2011;43(5). 2008;15(19):1887-1898. Laden BP, Porter TD. BMC Gastroenterol 2006;6:35. Int J Mol Med 2002;9:77-9. Yu, H. P., Hsu, J. C., Hwang, T. L., Yen, C. H., and Lau, Y. T. Resveratrol attenuates hepatic injury after trauma-hemorrhage via estrogen receptor-related pathway. Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D. Carcinogenesis 2007;28:922-31. View abstract. Wang Z, Huang Y, Zou J, et al. Scarlatti F, Sala G, Somenzi G, et al. View abstract. View abstract. Neurochem.Res 2008;33(12):2444-2471. Int.J.Cancer 5-1-2003;104(5):587-596. Life Sci. View abstract. Mndez-del Villar M, Gonzlez-Ortiz M, Martnez-Abundis E, Prez-Rubio KG, Lizrraga-Valdez R. Effect of resveratrol administration on metabolic syndrome, insulin sensitivity, and insulin secretion. JAMA Intern Med. SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Therapeutic potential of resveratrol: the in vivo evidence. View abstract. Fabbrocini, G., Staibano, S., De, Rosa G., Battimiello, V., Fardella, N., Ilardi, G., La Rotonda, M. I., Longobardi, A., Mazzella, M., Siano, M., Pastore, F., De, Vita, V, Vecchione, M. L., and Ayala, F. Resveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study. Novel insights of dietary polyphenols and obesity. Visit the FDA MedWatch website or call 1-800-FDA-1088. Anticancer Res. Drugs Exp Clin Res 1998;24:133-8. Evidence for a trade-off between survival and fitness caused by resveratrol treatment of Caenorhabditis elegans. 2015 Nov;123:15-21. 2003;17(4):307-313. Journal of Urology 2009;181(4). Taking resveratrol along with medications that also slow clotting might increase the chances of bruising and bleeding. A., Garcia-Conesa, M. T., Tomas-Barberan, F. A., and Espin, J. C. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial. Bost, J., Smoliga, J. M., Bost, K. M., and Maroon, J. C. Three Months Oral Supplementation of a Unique Polyphenol Mixture Improves Physical and Neurocognitive Performance Indicators in Sedentary Adults: 2205. Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases--safety, pharmacokinetics, and pharmacodynamics. Kimura, Y., Okuda, H., and Kubo, M. Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes. 2000;26(2):144-150. Vitis. Cancer Res. Cochrane Central Register of Controlled Trials 2010; Provinciali, M., Re, F., Donnini, A., Orlando, F., Bartozzi, B., Di Stasio, G., and Smorlesi, A. Chang, T. K., Lee, W. B., and Ko, H. H. Trans-resveratrol modulates the catalytic activity and mRNA expression of the procarcinogen-activating human cytochrome P450 1B1. View abstract. Cancer Prev.Res (Phila) 2011;4(9):1419-1425. Guarnieri, R., Pappacoda, A., and Solitro, S. [A resveratrol containing compound reduces oxidative stress and ameliorates clinical symptoms in COPD subjects] Un composto a base di resveratrolo riduce lo stress ossidativo e migliora la sintomatologia clinica in soggetti con BPCO. View abstract. View abstract. 10-22-2008;56(20):9362-9373. Carcinogenesis 1999;20:237-42. Inhibition of the expression of inducible cyclooxygenase and proinflammatory cytokines by sesquiterpene lactones in macrophages correlates with the inhibition of MAP kinases. Bertelli AA, Giovannini L, Giannessi D, et al. Diabetes 2011;60(2):634-643. Soleas GJ, Diamandis EP, Goldberg DM. Toxicol Lett 2001;125:83-91. Some medications changed by the liver include theophylline, omeprazole, clozapine, progesterone, lansoprazole, flutamide, oxaliplatin, erlotinib, and caffeine. View abstract. Gehm BD, McAndrews JM, Chien PY, Jameson JL. View abstract. Xenobiotica 2000;30(11):1047-1054. Ahmad KA, Clement MV, Hanif IM, Pervaiz S. Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution. Fan, E., Zhang, L., Jiang, S., and Bai, Y. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production. Gao X, Deeb D, Media J, et al. View abstract. 2001;299(3):874-882. Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship. Aggarwal, B. 1999;56(4):760-767. Wuertz, K., Quero, L., Sekiguchi, M., Klawitter, M., Nerlich, A., Konno, S., Kikuchi, S., and Boos, N. The red wine polyphenol resveratrol shows promising potential for the treatment of nucleus pulposus-mediated pain in vitro and in vivo. Copyright 2022 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. It is also used for symptoms of a lung disorder "chronic obstructive pulmonary disease" and to improve the health of the liver in people with liver damage not caused by drinking alcohol. Martinez, J. and Moreno, J. J. View abstract. Potter, G. A., Patterson, L. H., Wanogho, E., Perry, P. J., Butler, P. C., Ijaz, T., Ruparelia, K. C., Lamb, J. H., Farmer, P. B., Stanley, L. A., and Burke, M. D. The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1. Cancer Res. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. Some medications are changed and broken down by the liver. lifeirl resveratrol formulation View abstract. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. View abstract. resveratrol bluebonnet 500mg antioxidant View abstract. Insulin secretion and cyclooxygenase enzyme inhibition by cabernet sauvignon grape skin compounds. 2005;5(5):849-856. 2004;24(5A):2783-2840. Xuzhu, G., Komai-Koma, M., Leung, B. P., Howe, H. S., McSharry, C., McInnes, I. Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cells. Bournival, J., Quessy, P., and Martinoli, M. G. Protective effects of resveratrol and quercetin against MPP+ -induced oxidative stress act by modulating markers of apoptotic death in dopaminergic neurons. View abstract. View abstract. J Cardiovasc.Pharmacol. B., Bhardwaj, A., Aggarwal, R. S., Seeram, N. P., Shishodia, S., and Takada, Y. View abstract. View abstract. 1979;18:244-253. World J Gastroenterol. Effects of trans-resveratrol on copper-dependent hydroxyl-radical formation and DNA damage: evidence for hydroxyl-radical scavenging and a novel, glutathione-sparing mechanism of action. resveratrol olympian View abstract. Drug Metab Dispos. Jannin, B., Menzel, M., Berlot, J. P., Delmas, D., Lancon, A., and Latruffe, N. Transport of resveratrol, a cancer chemopreventive agent, to cellular targets: plasmatic protein binding and cell uptake. Hudson, G. M., Shelmadine, B., Cooke, M., Genovese, J., Greenwood, M., and Willoughby, D. S. Resveratrol Supplementation And Changes In Glucose, Insulin, And mRNA Expression Following Exercise In Overweight Females: 2467. resveratrol highest 500mg View abstract. Lee, J. E. and Safe, S. Involvement of a post-transcriptional mechanism in the inhibition of CYP1A1 expression by resveratrol in breast cancer cells. Huang C, Ma WY, Goranson A, Dong Z. Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway. Mueller SO, Simon S, Chae K, et al. 2000;7(4):312-321. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Biochem Biophys Res Commun 1996;226:810-8.. View abstract. View abstract. Int.J Tissue React. Antiplatelet activity of cis-resveratrol. Life Sci 10-11-2002;71(21):2489-2498. Li W, Seifert M, Xu Y, Hock B. Ciolino, H. P. and Yeh, G. C. Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. 10-17-2003;278(42):41482-41490. View abstract. resveratrol supplements 2012;67(12):1307-1312. 1999;889:214-223. J Biol Chem 2004;279:22727-37. J Clin Oncol 2001;19:2739-45. Grujic Milanovic, J., Mihailovic-Stanojevic, N., Miloradovic, Z., Jacevic, V., Milosavljevic, I., Milanovic, S., Ivanov, M., and Jovovic, D. J. RESVERATROL REDUCES BLOOD PRESSURE, CHANGES OF ANTIOXIDANT ENZYME ACTIVITY AND HISTOLOGICAL PARAMETERS IN EXPERIMENTAL MODEL OF MALIGNANT HYPERTENSION PP.29.171. Rocha-Gonzalez, H. I., Ambriz-Tututi, M., and Granados-Soto, V. Resveratrol: a natural compound with pharmacological potential in neurodegenerative diseases. Journal of Hypertension 2010;28. Menopause. Olas, B., Wachowicz, B., Bald, E., and Glowacki, R. The protective effects of resveratrol against changes in blood platelet thiols induced by platinum compounds. Wang, M. J., Huang, H. M., Hsieh, S. J., Jeng, K. C., and Kuo, J. S. Resveratrol inhibits interleukin-6 production in cortical mixed glial cells under hypoxia/hypoglycemia followed by reoxygenation. Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Oral resveratrol reduces neuronal damage in a model of multiple sclerosis. Comparison of the cardioprotective effects of red and white wines and their constituents: resveratrol, tyrosol, and hydroxytyrosol. Cavallaro, A., Ainis, T., Bottari, C., and Fimiani, V. Effect of resveratrol on some activities of isolated and in whole blood human neutrophils. Life Sci. View abstract. Rosa, F. T., Zulet, M. A., Marchini, J. S., and Martinez, J. 6-7-2005;11(21):3171-3174. Resveratrol in raw and baked blueberries and bilberries. View abstract. Clin Hemorheol Microcirc. Biochem.Pharmacol. Br J Nutr. View abstract. Vitrac, X., Desmouliere, A., Brouillaud, B., Krisa, S., Deffieux, G., Barthe, N., Rosenbaum, J., and Merillon, J. M. Distribution of [14C]-trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration. View abstract. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. View abstract. View abstract. Biochem.Pharmacol. www.ars-grin.gov/duke (Accessed 3 November 1999). Kozuki Y, Miura Y, Yagasaki K. Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action.Cancer Lett 2001;167:151-6. Rahman, I. Antioxidant therapeutic advances in COPD. Trincheri NF, Nicotra G, Follo C, et al. Bowers JL, Tyulmenkov VV, Jernigan SC, Klinge CM. View abstract. Cell Metab. Boca Raton, FL: CRC Press, 2005. Clin Chim Acta 1995;235:207-19. Br.J.Pharmacol. Shindler, K. S., Ventura, E., Dutt, M., Elliott, P., Fitzgerald, D. C., and Rostami, A. View abstract. Am.J.Physiol Gastrointest.Liver Physiol 2002;282(5):G809-G816. Liu K, Zhou R, Wang B, Mi MT. Spine (Phila Pa 1976.) Some people apply resveratrol to their skin to treat acne. Arterioscler.Thromb.Vasc.Biol 1999;19(2):419-426. Piver, B., Berthou, F., Dreano, Y., and Lucas, D. Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages. Almeida, L., Vaz-da-Silva, M., Falcao, A., Soares, E., Costa, R., Loureiro, A. I., Fernandes-Lopes, C., Rocha, J. F., Nunes, T., Wright, L., and Soares-da-Silva, P. Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers. Kim YA, Choi BT, Lee YT, et al. View abstract. View abstract. Jacobson JS, Troxel AB, Evans J, et al. Zhang, H., Zhang, J., Ungvari, Z., and Zhang, C. Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress. 2008;9 Suppl 2:S6. Drugs Exp Clin Res 1996;22:61-3. (detailed description of each of the ratings). Oncogene 2004;23:9247-58. A., and Tredici, G. Anti-apoptotic effect of trans-resveratrol on paclitaxel-induced apoptosis in the human neuroblastoma SH-SY5Y cell line. View abstract. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others. Elmali N, Baysal O, Harma A, et al. Gen Pharmacol 1996;27:363-6. View abstract. Molnar, V. and Garai, J. Plant-derived anti-inflammatory compounds affect MIF tautomerase activity. Dietary resveratrol does not affect intestinal tumorigenesis in Apc(Min/+) mice. View abstract. View abstract. Biochem.Mol.Biol.Int. View abstract. View abstract. View abstract. Lin, J. K. and Tsai, S. H. Chemoprevention of cancer and cardiovascular disease by resveratrol. Dong, W., Li, N., Gao, D., Zhen, H., Zhang, X., and Li, F. Resveratrol attenuates ischemic brain damage in the delayed phase after stroke and induces messenger RNA and protein express for angiogenic factors. 2010;91(6):1590-1597. J Agric Food Chem 2004;52:935-42. Resveratrol might decrease how quickly the liver breaks down some medications. Some medications changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), zileuton (Zyflo), zolmitriptan (Zomig), and others. View abstract. Resveratrol: a polyphenol for all seasons. Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. J Med Food 2008;11(4):610-614. 2014 Jun;99(6):1510-9. Clin Biochem 2003;36:79-87.. View abstract. 2014 Oct;34(10):837-43. View abstract. Jang M, Cai L, Udeani GO, et al. View abstract. In children, resveratrol is POSSIBLY SAFE Crit Care Med 2010;38(4):1147-1154. Rakici, O., Kiziltepe, U., Coskun, B., Aslamaci, S., and Akar, F. Effects of resveratrol on vascular tone and endothelial function of human saphenous vein and internal mammary artery. 10-15-2001;62(8):1113-1124. resveratrol reserveage caps mg cellulose vegetable capsule silica dicalcium stearate magnesium phosphate shell ingredients 2009;29(8):1164-1171. 8-1-2012;110(3):356-363. B., and Xu, D. Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. View abstract. 60ct 500mg resveratrol Resveratrol improves health and survival of mice on a high-calorie diet. View abstract. Life Sci. Nutr Rev. View abstract. Br.J.Cancer 3-4-2002;86(5):774-778. 2010;49(7):449-454. resveratrol The Sciences and Engineering. View abstract. 10-23-2012;8(5):790-793. Howitz, K. T., Bitterman, K. J., Cohen, H. Y., Lamming, D. W., Lavu, S., Wood, J. G., Zipkin, R. E., Chung, P., Kisielewski, A., Zhang, L. L., Scherer, B., and Sinclair, D. A. Am J Clin.Dermatol 4-1-2011;12(2):133-141. Shishodia S, Aggarwal BB. 500mg resveratrol Br.J.Pharmacol. Creasy LL, Coffee M. Phytoalexin production potential of grape berries. View abstract. View abstract. View abstract. View abstract. In theory, taking resveratrol along with some medications that are broken down by the liver may increase the effects and side effects of some medications. View abstract. View abstract. Howells, L. M., Berry, D. P., Elliott, P. J., Jacobson, E. W., Hoffmann, E., Hegarty, B., Brown, K., Steward, W. P., and Gescher, A. J. 2004;63(2):85-95. 2006;5(6):493-506. Patel, K. R., Brown, V. A., Jones, D. J., Britton, R. G., Hemingway, D., Miller, A. S., West, K. P., Booth, T. D., Perloff, M., Crowell, J. Davy BM, Melby CL, Beske SD, et al. Basly, J. P., Marre-Fournier, F., Le Bail, J. C., Habrioux, G., and Chulia, A. J. Estrogenic/antiestrogenic and scavenging properties of (E)- and (Z)-resveratrol. A. Bioactive compounds with effects on inflammation markers in humans. View abstract. Biochem Pharmacol 2003;66:2427-35. Int.J.Oncol. Resveratrol is a peroxidase mediated inactivator of COX-1 but not COX-2: A mechanistic approach to the design of COX-1 selective agents. resveratrol lifeirl nutrica 2014 Dec;12(12):2092-103.e1-6. A., and Das, D. K. Does white wine qualify for French paradox? Toxicology 8-7-2000;148(2-3):187-197. Gruber, J., Tang, S. Y., and Halliwell, B. View abstract. 10-1-2011;36(21):E1373-E1384. Wang S, Moustaid-Moussa N, Chen L, Mo H, Shastri A, Su R, Bapat P, Kwun I, Shen CL. View abstract. 2001;37(3):262-270. View abstract. Higher doses of up to 3000 mg have been taken by mouth safely for up to 8 weeks. Absorption of three wine-related polyphenols in three different matrices by healthy subjects. Baur JA, Pearson KJ, Price NL, et al. The Sciences and Engineering 2009;70(4-B). View abstract. J Alzheimers.Dis 2010;19(1):11-26. View abstract. View abstract. 2003;23(4):1143-1149. View abstract. Cell Metab 2008;8(2):157-168. Miraglia Del Giudice M, Maiello N, Capristo C, Alterio E, Capasso M, Perrone L, Ciprandi G. Resveratrol plus carboxymethyl--glucan reduces nasal symptoms in children with pollen-induced allergic rhinitis. 2014 Jul;174(7):1077-84. View abstract. Kim, Y. 4-13-2001;302(1):41-44. 2014 Jan;25(1):1-18. Comparative study of estrogenic potencies of estradiol, tamoxifen, bisphenol-A and resveratrol with two in vitro bioassays. when sprayed in the nostrils for up to 2 months. J Agric.Food Chem 3-26-2003;51(7):1850-1857. View abstract. Resveratrol is LIKELY SAFE

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