The reverse-phase chromatography is just one option available to researchers to provide separation of lipid species prior to analysis by MS. An alternative approach we have employed in the laboratory is to make use of HILIC. I get mine from a local Co-op Pharmacy, and its 98% pure or better. We use cookies to help provide and enhance our service and tailor content and ads. Sadly, the Jessops product does not give a purity percentage on the packaging. we use this stuff in the lab as a general disinfectant, and always have to be careful about the dilutions. It's easy! Over 12,000 isopropanol exposures among children up to 19 years of age were reported to the AAPCC in 2003.1 Isopropyl alcohol toxicity may occur via the dermal and inhalation routes, such as may result during misguided sponge baths for fever. Just order it one day, and get it the next. Why not try some Baader Optical Wonder fluid ? Phenolics or quaternary ammonium compounds are added at levels under 1% in this application. It is the second most commonly ingested alcohol after ethanol. Commercial formulations with high levels of alcohol are typically in the form of aerosol sprays, and are in combination with other disinfectants for greater efficacy. No Co-Op pharmacy around here, that I know of Will try further afield to check - thanks for the suggestion. Not that I'm endorsing such things - Well, much anyway Good to hear from you.., thanks for that information. with 75% alcohol by Rhinestone, Covidien 5110 Webcol Alcohol Prep, 2-Ply, Large (Pack of 200), Curad Alcohol Prep Pads, 70% Alcohol, 1000 Count (5 Boxes 200 CT/EA), The Honest Company Sanitizing Alcohol Wipes, Unscented, 150 Count, TOPCO Alcohol Prep Pads, (5 Packs of 100), COVIDIEN 6818 Webcol Alcohol Prep, Sterile, Medium, 2-Ply (Pack of 200), Amazon Brand - Solimo 50% Isopropyl Alcohol First Aid Antiseptic, 16 Fl Oz (Pack of 12), MENDA 35299 High-Density Polyethylene/Hdpe/Steel/Ldpe/Low-Density Polyethylene Dispensing Bottle, One-Touch Liquid Dispenser Pump, Printed"IPA", 6 oz, 16 fl. Alcohols are believed to function by denaturing proteins, which is dependent on the relative amounts of alcohol and water [22]. :mrgreen: N.B. Altered mental status, when it occurs, typically manifests within 2 hours of ingestion.4 Hypotension may occur due to diuresis, peripheral vasodilation, and myocardial depression. Edward Fu, Diane Boesenberg, in Handbook for Cleaning/Decontamination of Surfaces, 2007. A highly efficacious pediculicide based on dimeticone: Randomized observer blinded comparative trial.Infectious Diseases, 8, 115. The chromatographic method is as follows: The entire lipid extract was dissolved in 500l 1:1 methanol/chloroform containing 100M (PC 34:0) phosphatidylcholine (Avanti Lipids Inc., Alabaster, AL, Unites States). Isopropanol is twice as potent as ethanol in terms of CNS depression. Household vinegar and isopropyl alcohol can be used to inactivate the toxin. Ethanol-like inebriation occurs, with an acetone odor to the breath, gastritis, occasionally with hematemesis, acetonuria, and acetonemia without systemic acidosis. Symptomatic patients with concentrations greater than 100mg/dL require at least 24 hours of close observation for resolution and should be admitted. You get the ultra pure stuff on Ebay, why do you want it anyway? Wash hands frequently as soap and alcohol gel can kill the virus. Children are especially susceptible to systemic symptoms from the dermal application of IPA used to reduce fever. Hill, N., Moor, G., Cameron, M. M., et al. oz. Hypotension and hypothermia can occur with very large ingestions. See how a store is chosen for you. Avoid sharing clothes or belongings as the virus remains active on items. I have a 250ml bottle of Ambersil IPA you can have , (unopened). Isopropanol can be found in rubbing alcohol, solvents, and lacquer thinner. we get ours from medical sales at 100% concentration and have to dilute it down per use, but it should be freely available, as others have said. David A. Provenzano MD, Timothy R. Deer MD, in Essentials of Pain Medicine (Fourth Edition), 2018, Antiseptic solutions containing isopropyl alcohol, povidone-iodine, and/or chlorhexidine gluconate are most commonly used for patient skin preparation. Acetone is metabolized to acetol (hydroxyacetone) by acetone monooxygenase (seeFig. There may be advice on the container to that effect I think. I have always used IPA. 71.2).25, Treatment of isopropanol poisoning is largely supportive.28 Hemodialysis can be initiated to enhance elimination of the parent drug but is rarely indicated because patients rapidly improve with supportive care alone.2930 Furthermore, there is no definitive clinical evidence that hemodialysis improves patient outcome in severe isopropanol poisoning.30, Lee D. Roberts, Julian L. Griffin, in Methods in Enzymology, 2014. Gastritis is common after ingestion. I use this on my corrector plate and it comes up fantastic each time. TheIsopropyl Alcohol 91% is anuncomplicated formula that makes this a consistent and dependable medicine cabinet staple. By But I've seen links posted for stuff on eBay that were much cheaper. Exposures to IPA reported to US poison centers have ranged from about 15,000 to 21,000 cases/year.3,18 In 2013, 15,454 single substance exposures occurred, with 85% unintentional in nature, 4% having moderate to major effects, and three deaths, reflecting a low case-fatality rate.3. Loss of consciousness is associated with respiratory depression, hypoxia, and aspiration pneumonitis. Isopropyl alcohol metabolizes to acetone. IPA is listed on what they call the General Sales List and has no medical or ethical sales restrictions on it (she thought it might as it was an alcohol). Myoglobinuria can cause ARF. Supportive treatment is similar to that for ethanol ingestions. I'm sure I read somewhere that there were health risks and it is better diluted (with distilled water) anyhow. Acetone can also contribute to CNS depression. Apply a small amount to cuts and scrapes to disinfect the area, understand the severity of the injury and prevent future infections while you treat wounds. Search: Clean Carts Vapes Or you can soak it in isopropyl alcohol and dry it when you install Then, try to use cotton or q-tip with isopropyl alcolhol to clean your device Manchester United drop points for the third time in four Premier League games with a goalless draw against under-strength Arsenal Voltage Setting: The Magneto has a single voltage setting, but its exact number is unknown, since Yocan does not release that information Blinking vape pen not pulling or shorted Voltage Setting: The Magneto has a Product ID : YOCAN-HIT-MOUTHPIECE-PACK-5 Do not allow the lightweight feeling of the device to distract from the sturdy quality 1 x Yocan UNI Pro Box Yocan Regen Quartz Tri Coil (5 Pack) $20 30) SKU: ONT017152 Search: Yocan Uni Blinking 5 Times Fix The ceramic convection-style oven allows dry herb to be vaporized without reaching the point of combustion promoting clean and smooth vaporization of your dry herb without the burnt The Yocan Hit vaporizer is a portable device with an effective way to vaporize dry herb with a clean conduction method 1 x Yocan Evolve Plus Mouthpiece & Pre-Installed Dual Quartz Coil & Cap (for wax and concentrates) 1 x Yocan HIT Vaporizer; 1 x Cleaning Brush; 1 x USB-C Charging Cable; 1 x User Manual; Budget dry herb vapes are pretty simple to use (You save $7 This means that when using the Yocan HIT Vaporizer youll be able to experience the terpenes and the best your herbs have to offer In The Box 1 Yocan Hit Replacement Mouthpiece We Also Recommend Yocan Torch XL 2020 Version Portable Wax eNail $7499 Yocan UNI Wax Cartridge VV Box Mod Replacement Parts Available for the Yocan HIT: Yocan HIT Replacement Mouthpiece (click here) Yocan HIT / Torch XL / UNI S / Vane / X Replacement Type-C Charging Cable (click here) Weight. Metabolism occurs primarily in the liver by ADH into acetone. Further metabolic products include propylene glycol, methylglyoxal, lactate, formate, and acetate. (2008). Capacity,Brown, Suave Hand Sanitizer Alcohol Based Kills 99.9% of Germs 10 Fl Oz (Pack of 6), Purell Advanced Hand Sanitizer Refreshing Gel, Clean Scent, 8 fl oz Pump Bottle (Pack of 12) - 9652-12, Dynarex 1116 Dynarex Sterile Alcohol Prep Pad - 1,000 ct - Large by Dynarex, Curad Alcohol Disinfectant Prep Pads, 2-ply, Medium Size, 200 Count, Gotparts747 High Purity Isopropyl Alcohol USA, High Purity Isopropyl Alcohol - Made In America, Quality alcohol pads at affordable prices. Burgess, I. F., Lee, P. N., & Matlock, G. (2007). I use it to clean my filters and wondered if I should be diluting it with distilled water for this purpose? Connolly, M. (2003). We have placed cookies on your device to help make this website better. The CNS depressant potency is twice that of ethanol. It inhibits gluconeogenesis.Normal propyl alcohol is related to isopropyl alcohol but is more toxic. Normal clothing and petrolatum jelly applied to the skin do not reliably prevent stings. Avoid touching animals that can be monkeypox carriers, especially imported rodents like rats and rabbits. I was told they got a "bit of a talking to", from the local Bobby, when they tested their "Supergun", on the local allottments. Burgess, I. F., Brown, C. M., & Lee, P. N. (2005). ADH inhibition increases the half-life to 16 to 27 hours.18 Elimination primarily occurs via the kidneys, with up to 20% of IPA excreted unchanged in the urine. Contact time is, however, 15 minutes. Time is fleeting. Isopropyl alcohol is rapidly absorbed from the GI tract; peak plasma concentrations occur within 30 minutes. Monitoring of blood isopropyl alcohol levels (not readily available in all institutions), acetone, glucose, and ABG should be maintained. ScienceDirect is a registered trademark of Elsevier B.V. ScienceDirect is a registered trademark of Elsevier B.V. https://doi.org/10.1371/journal.pone.0001127, Depression of the CNS occurs: lethargy at blood, Iatrogenic and Poison-Derived Acid Base Disorders, Methods of Adipose Tissue Biology, Part B, Chemical Disinfection of Hard Surfaces Household, Industrial and Institutional Settings, Handbook for Cleaning/Decontamination of Surfaces, Interventional Pain Procedures and the Risk of Infection, Essentials of Pain Medicine (Fourth Edition), Pediatric Clinical Advisor (Second Edition). Capacity, Blue, Prove Sterile Alcohol Prep Pads Wipes Medium 2-Ply Wipes, 200 Count (Pack of 1), Beauticom 9 oz ALCOHOL Labeled Push Down Liquid Pumping Dispenser Empty Bottle, Professional, Personal, Laboratory, Dentist, Salon, Nail Care, Hospital use (9 oz, Gray w/Alcohol Imprinted), MEDca Alcohol Prep Pads, Sterile, Medium, 2-Ply (Pack of 300), MG Chemicals 824 99.9% Isopropyl Alcohol Electronics Cleaner, 4.25 Fl Oz, Curad Alcohol Prep Pads 200 Ea (Pack Of 2), 25 x 950ml Bottles of 99.8+% Pure Isopropyl Alcohol Industrial Grade IPA Concentrated Rubbing Alcohol, 32.12 Fl Oz (Pack of 25), Wash Bottle for Isopropanol, 500ml - Labeled with Color Coded Chemical & Safety Information (2 Color) - Wide Mouth, Self Venting, Low Density Polyethylene - Eisco Labs, 91% Isopropyl Alcohol 32 fl oz Bottle (2 Bottles), Pharma-C-Wipes 70% Isopropyl Alcohol Wipes (Case of 6 Canisters) MADE IN THE USA, 365 by WFM, Isopropyl Alcohol 70%, 16 Fl Oz, ForPro 99% Isopropyl Alcohol (IPA), Pure & Unadulterated Concentrated Alcohol, 32 Ounces, Rayson Empty Spray Bottle Refillable Container, Fine Mist Sprayer Trigger Squirt Bottle for Taming Hair, Hair styling, Watering Plants, Showering Pets (1 Pack, Green), SP Bel-Art Safety-Labeled 4-Color Isopropanol Wide-Mouth Wash Bottles; 500ml (16oz), Polyethylene w/Yellow Polypropylene Cap (Pack of 4) (F11716-0008), Hydrox 70% Isopropyl, Rubbing Alcohol, 16 oz, MG Chemicals - 824-1L 99.9% Isopropyl Alcohol Electronics Cleaner, 945 mL (1 Quart) Liquid Bottle, Reagent Grade Denatured Ethyl Alcohol, Anhydrous - 100% Alcohol, 1L - Denatured with Isopropyl Alcohol & Methanol - The Curated Chemical Collection - Not for Use on Body or Skin, Purell Advanced Hand Sanitizer Refreshing Gel Design Series, Clean Scent, 8 Fl Oz Pump Bottle (Pack of 4) - 9652-06-ECDECO. Hemodialysis is warranted in cases of life-threatening overdose but is rarely needed. Wear a face mask when in crowded areas monkeypox can be transmitted via saliva droplets. If the patient is hypoglycemic, hypotensive, or comatose, he or she should be admitted to the intensive care unit. He also pointed out that the disease is no longer endemic to Africa because most patients have not travelled there before. (2005). IPA is found in numerous household and commercial products, including rubbing alcohol, antifreeze, disinfectants, cleaning solutions, skin and hair products, and hand sanitizers. I second Kai's recommendation. (2009). astro84, A nephrologist should be consulted if the blood isopropanol plasma concentration is greater than 250mg/dL. Injuries from prolonged immobilization with CNS depression can lead to compartment syndrome and rhabdomyolysis. Other vendor software can be used as well as open-source software such as XCMS (http://metlin.scripps.edu/xcms/) and MZmine 2 (http://mzmine.sourceforge.net/). The absence of excess acetone in the blood (normal is 0.3 to 2mg/dL) within 30 to 60 minutes or excess acetone in the urine within 3 hours excludes the possibility of significant isopropanol exposure. It is what I was advised by a chemist. Swimmers should obey all posted warnings, and children should be watched carefully along the beach. I have just spoken to my old friend who is a Hospital Pharmacist. 12.2. Notice the different order of lipid classes separated compared with the reverse-phase method in Fig. Update on treatments for head lice,Drug Ther Bull.47, 5052. By continuing you agree to the use of cookies. I must admit, my last foray into BOOTS was unsuccessful and I too received "the look". Rick D. Kellerman MD, in Conn's Current Therapy 2021, 2021. oz. SeeTable 10 for ethanol features of alcohols and glycols. (2005). Analysis of intact lipids was performed using a Waters QToF Xevo (Waters Corporation, Manchester, United Kingdom) in combination with an Acquity UPLC. Isopropyl alcohol (isopropanol) which is widely used as organic solvent and is a component of rubbing alcohol, can also be abused for intoxication purpose. Typical LCMS chromatogram of intact lipids extracted from white adipose tissue of rats and analyzed according to the methods earlier for reverse-phase chromatography (1.7m bridged ethyl hybrid C8 column). Yes, indeed I intend on diluting with distilled water - in the proportions advised as suitable for cleaning the front corrector of my SCT. IPA follows first-order kinetics, with a half-life of 2.5 to 8 hours. Note: The serum isopropyl concentration and amount ingested can be estimated using the same equation as is used in ethanol kinetics and substituting the specific gravity of 0.785 for isopropyl alcohol. Hand Sanitizer alcohol Wipes, [2-Pack] 50 pc. undefined out of 5 stars with undefined reviews, Isopropyl alcohol solution is a first aid antiseptic, Prevent infection in minor cuts, scrapes and burns, An essential medicine to keep in your home, If youre not satisfied with any Target Owned Brand item, return it within one year with a receipt for an exchange or a refund. In a post on the Blockdit platform on Sunday, the doctor said more than 16,000 people in 75 countries have been infected with monkeypox since May this year. While this approach does not separate out triacylglycerides as well as the reverse-phase chromatography detailed earlier, it does separate out better lipid classes. Someone will follow with the link shortly, I'm sure! Copyright 2022 Elsevier B.V. or its licensors or contributors. Hypoglycemia has not been reported with IPA as it has for other alcohols. Patient care is supportive. Comparison of wet combing with malathion for treatment of head lice in the UK: A pragmatic randomised controlled trial.Lancet, 356, 540544. Isopropanol is a gastric irritant. All swimmers should be aware of the risks posed by marine stings. Content on this site is for reference purposes only. In addition to an osmolal gap (see Table 134-1), ketonemia or ketonuria may occur. Divers should avoid handling corals and sponges unless proper protective clothing is worn. Volume distribution is 0.6kg/L. Occupational exposures to isopropyl alcohol vapors have been reported to cause eye irritation but no significant injury. I get it from my local Pharmacy no problemo. Isopropyl alcohol is well known to cause ocular surface irritation, epithelial keratitis and occasional corneal abrasion. The pharmacist at my local boots had that "We don't hear that one often" look on his face, but got a bottle ordered for the next day, at the outlandish price of 6 (500ml). Gastrointestinal decontamination has no role in the treatment of isopropanol ingestion. Devin Gattey MD, in Clinical Ocular Toxicology, 2008. On occasion, manufacturers may improve or change their product formulas and update their labels. If this is done before the alcohol has completely dried, a familiar round epithelial defect, a burning sensation or frank eye pain may ensue. I feel much more comfortable washing my mirror in water than alcohol. A concomitant respiratory depression can occur with profound CNS depression. Avoid picking the nose, rubbing eyes or putting a hand in the mouth as the virus can enter that way. Burgess, I. F. (2009). BH Supplies Alcohol Prep Pad Sterile, Medium 2-Ply, 400 count - Saturated With 70% Alcohol, BH Supplies Alcohol Prep Pad Sterile, Medium 2-Ply, 100 count - Saturated With 70% Alcohol, Amazon Brand - Solimo Hydrogen Peroxide Topical Solution USP, 32 Fl. TheIsopropyl alcohol 91%treats a number of ailments that require the antiseptic properties of rubbing alcohol. Apparently it WORKED though, blew a "U2" battery straight through some old bloke's corrugated iron shed at 50 yards! As IPA is one of the primary "antiseptics" used against MRSA then any decent pharmacy should stock it or be able to source it. However, the use of chlorhexidine for spinal anesthesia has not been shown to increase neurologic complications.78 The use of chlorhexidine prior to epidural catheterization has been shown to be superior to povidone-iodine in reducing catheter colonization rates.79 Although there are no studies directly comparing infection rates with the use of chlorhexidine gluconate versus povidone-iodine for interventional pain procedures, based on extrapolation of data from other surgical subspecialties, chlorhexidine-based products may offer improvement in infection control rates. Oral ingestion is the major route of exposure, but absorption can occur transdermally, rectally, or via inhalation. try not to use it in a confined and unventilated space You need to be a member in order to leave a comment. The only thing I haven't used it on is the objective lens of my scope. For interventional pain procedures, the US Food and Drug Administration has not approved the use of chlorhexidine for neuraxial procedures due to a lack of clinical safety trials. The osmolal gap increases 1mOsm per 5.9mg/dL of isopropyl alcohol and 1mOsm per 5.5mg/dL of acetone. Avoid touching others as monkeypox can be transmitted via blisters or pus. Where do I get Isopropyl alcohol (IPA)???? Ive got some, I used it on my glasses first, then have used it on all my gear, camera the works. Ethyl alcohol, iso-propyl alcohol and n-propyl alcohol possess very good disinfectant properties in the range of 6090% solutions with water. Sampling cone and capillary voltages were 30V and 3kV. CNS depression ranges from lethargy to stupor or coma. The airway must be protected with intubation, and assisted ventilation administered if necessary. I tried Boots, Superdrug, and two other independent pharmacies, but each of their respective pharmicists either looked at me as if I was asking for heroin , or promptly said that they didn't sell the thing.i, Given that this_is "rubbing alcohol" we're talking about, I'm not confident that even if they did tell me that they do have this, that they'd be able to, or be honest in telling me that its 90% + or not. Single blind, randomised, comparative study of the Bug Buster kit and over the counter pediculicide treatments against head lice in the United Kingdom.BMJ, 331, 384387. Not sure how pure it would be getting it of ebay. Powered by Invision Community. Oz (Pack of 6), MENDA 35608 Glass/Polypropylene/Steel/Low-Density Polyethylene/Ldpe Dispensing Bottle, Lasting-Touch, Imprinted 'Alcohol', Amber Round Glass 8 oz., 8 fl. Perfume and highproof liquor may be less efficacious and may be harmful. Ketosis without acidosis is a classic finding in IPA ingestion. They are considered intermediate-level disinfectants, effective against vegetative bacteria, enveloped viruses, and some fungi and mycobacteria, including M. tuberculosis. http://www.firstlightoptics.com/proddetail.php?prod=wonderfluid. Does anyone know where its possible to get Isopropyl alcohol (or IPA) that's 90% or better in the UK, please? William T. Tsai MD, Robert J. Freishtat MD, MPH, in Pediatric Clinical Advisor (Second Edition), 2007. Dr Chalermchai, however, said monkeypox was not as worrisome as Covid-19 as this virus does not spread that quickly. Hypotension signifies severe poisoning with increased mortality risk. If the patient is hypoglycemic, glucose should be administered. Another potential route of ocular injury includes pre-surgical preparation of the peri-ocular skin with alcohol wipes. It is metabolized to acetone, a CNS and myocardial depressant. Top subscription boxes right to your door, 1996-2022, Amazon.com, Inc. or its affiliates. The binary solvent system (flow rate 0.400ml/min) employed a gradient of solvent A (HPLC-grade acetonitrile/water 60:40, 10mM ammonium formate) and solvent B (LCMS-grade acetonitrile/isopropanol 10:90, 10mM ammonium formate). We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. Alcohols can also be used as cosolvents in pine oil or phenolic formulations that bloom, or emulsify rapidly, upon dilution in water. Most commonly, isopropyl alcohol comes into contact with the eye surface during Goldmann applanation tonometry. Discover more about the small businesses partnering with Amazon and Amazons commitment to empowering them. Recommended management of headlice and scabies.The Prescriber, 2013, 1729. Just pm your details please. The data were collected in positive and negative modes with a mass range of 1001200m/z, a scan duration of 0.2s, and an interscan delay of 0.014s. The source temperature was set at 120C and nitrogen was employed as the desolvation gas (600l/h) at 280C. He also noted that there are plenty of vaccines and drugs that can deal with monkeypox effectively. Triacylglycerol species are highlighted with a panel displaying the mass spectrum for a selected chromatographic peak. Heukelbach, J., Pilger, D., Oliveira, F. A., et al. From: Essentials of Medical Biochemistry, 2011, Ron M. Walls MD, in Rosen's Emergency Medicine: Concepts and Clinical Practice, 2018, Isopropyl alcohol (IPA; isopropanol, 2-propanol, CAS 67-63-0, C3H7OH) is a clear, colorless liquid with a fruity odor and slightly bitter taste. Your recently viewed items and featured recommendations, Select the department you want to search in, Amazon Brand - Solimo 99% Isopropyl Alcohol For Technical Use,16 Fl Oz. Call it 5 inc postage. The only thing to guard against, apart from drinking the stuff, is do not inhale the fumes, especially if you are in a confined area. Sign up for a new account in our community. Climate Pledge Friendly uses sustainability certifications to highlight products that support our commitment to help preserve the natural world. A lysophosphocholine C17:0 internal standard (in IPA/methanol/water ratio 2:1:1) was spiked into each sample to give a final concentration of 20M. Jessops sell it - I bought some from them recently, Bells factory top of international drive Orlando stock it. If it's to clean a mirror then pop along to your local tropical/marine shop and see if they sell RO water. Acetone reaches a peak plasma concentration from 7 to 30 hours postexposure and has a half-life of up to 24 hours. If the item details above arent accurate or complete, we want to know about it. Tonometer tips are frequently cleaned with a wipe saturated in 70% isopropyl alcohol or soaked for at least 5 minutes in a 70% solution (the method recommended by the US Center for Disease Control) and applied to the corneal surface. Each peak was detected based on a mass window of 0.05Da and retention time window of 6s. The peaks were normalized to the internal standard and deisotoped. Burgess, I. F., Brown, C. M., Peock, S., et al. The gradient started at 30% B, reached 99% B over 18min, and then returned to the starting conditions for the next 2min. Headache, dizziness, ataxia, hypotonia, hyporeflexia, dysarthria, and seizures have been reported.18 Pupil size is variable, but miosis is commonly observed. Diagnosis of isopropanol ingestion relies on astute history and physical examination, laboratory values that are significant for an elevated urine acetone level, and a wide serum osmolar gap.25 Interestingly, unlike the other toxic alcohols and their metabolites, which produce large anion gap metabolic acidosis, isopropanol is metabolized by alcohol dehydrogenase to its metabolite, acetone, which does not cause an anion gap metabolic acidosis and cannot be metabolized to a compound that does.2627 As such, treatment with fomepizole, an alcohol dehydrogenase competitive inhibitor, actually prolongs the effect of isopropanol, because isopropanol cannot be metabolized to its byproduct for elimination (Fig.
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