endobj False x+T5363P0 BCc=3@D!9W3P% endstream endobj 5 0 obj 11 endobj 6 0 obj << /Length 5 0 R /Filter /FlateDecode >> stream Yq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXY Si'`Ou}J4^1o>e7,%~(@aa\p)%-Z$!\?.w#g0?J Fuo4|j|l itK0zY=)NE,+c|2H`gNJW h&2x_]g4vo0s A8BMc{_0'k$.vg'efc(u[;WsQg>'#e_,5 Release behavior and signaling effect of vitamin D3 in layered double hydroxides-hydroxyapatite/gelatin bone tissue engineering scaffold: An in vitro evaluation. q7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq x\r:OUTB$wjjvM23sH$HTghrkA):g+FngRe9?.bCy_WgoL+iSu~W_'Wl@jNi4`S6i}Li6Q7(f'kZO2Vj#=0mfR0}I".^(q;M5ja"~x.*Xi(FfFVUTNjjM _V4=RPkrJ9BP4'm',j~rR8+'ugZ" /Q4L>uqx0LuBD^8$h2D^F"b2(uB {IeY"B/4{4tD{+[4 =wUM[MXtpd(\6WZGMvt@tJnP kUf{_.o. ad*S/k #l? ==V>v?NwV~oWY;A,]Y a0uoooG[uX~0~j[o^ ww^vKow_{].(uZ|o{V7[z}t/=wMoV}ohm}v+aaUUMjxEA6`tW[vG q7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq @u a pc application/pdf endobj 0000002221 00000 n As orally administered pill often will not dissolve at exactly the right site in the gastrointestinal tract where the medicine can be absorbed into the bloodstream, a new drug delivery system developed which includes magnetic pill which solve the problem by safely holding a pill in place in the intestine wherever it needs to be. QuarkXPress(tm) 6.1 View 2 excerpts, references background and methods. Yq7FXYqlfmI+Z/0ev+GxZHUPVTl+kTKIfRr+8p6ILc/5e2KrPLv+LfRm/wARmw9bkPq4071uPGm/ XYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FX uuid:2b483b49-92b7-1741-ab43-a42aed2b1199 Black In this. 2 0 obj x+T5333P AsK=C3SD!9W3P% f endstream endobj 148 0 obj 11 endobj 149 0 obj << /Length 148 0 R /Filter /FlateDecode >> stream False endobj "_^](;}@k)de:hA7jy~WgE;r -K|BLBI CuNK?GR(Z2% =6h5x !#gr:!az`;kO$ r\8}[!.#3ff]*a 0X`==HZm%GfNL*< \!^|fvK'Zq3,O7T[2o#D/=_~q&LhU=o(; Pjx~Yh{'Vv;4Aya~{>sbTr :BqQsPw7F !|/}Y'f`B;c%eh:xD2##q/J*$?0(%c:Pjp|cV[ CS=09S^bF!:guM>lz"Y0:m$2rq#{(\N3 3}(|?idkY. -N?fJSKPrn*!(R,gjAMA"?4w.S%P@< `IVAA$B 2& h3Ha Ld&q.Jg!Ak P24"74 bBC0Hg ]Li [TC\H" >`> VCh7pUiO! vCh"{v6"j2 L0 r m8+m A`lRh d8`l26Xl8!20L,"P0!p`0Vh&mAP8a@&6 L6 C=Va Magenta {lurp!%LQYVT8AO;5(!HDDDDDGB-4tfFDE#i^maWUdIEpM|/GH8B"C W"""""C-Md2!+eLrrFcJAM0"""""""""#;RkqZ*G 5voQhX~LaMV?Tjikk?CVhp w endstream endobj 1 0 obj << /Type /Page /MediaBox [ 0 0 636 814 ] /Parent 140 0 R /Resources << /XObject << /Im1 8 0 R >> /ProcSet 150 0 R >> /Contents 2 0 R /CropBox [ 0 0 636 814 ] /Rotate 0 >> endobj 2 0 obj [ 4 0 R 6 0 R ] endobj 3 0 obj 43 endobj 4 0 obj << /Length 3 0 R /Filter /FlateDecode >> stream 0000007746 00000 n 1 0 obj /9j/4AAQSkZJRgABAgEASABIAAD/7QAsUGhvdG9zaG9wIDMuMAA4QklNA+0AAAAAABAASAAAAAEA Regular Yq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXY 2 0 obj AQBIAAAAAQAB/+4ADkFkb2JlAGTAAAAAAf/bAIQABgQEBAUEBgUFBgkGBQYJCwgGBggLDAoKCwoK XYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FX Yq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXY Default Swatch Group 5cf)oi[ )XHJn?S&c{+.?Md ] K/LNDz9c\q..#FFe_7{> +K)R \axj*t_S9F/;M10rUYE+BkCdE /UmEZv2A/.<3f{IH,#y=48_|J' F)qEV;m$xs|y?w=X)0(-:)kzq=ceUyq0ffyl7Z'zLKFcH}$0$0R=rXE]=tw;|~}NRGx^8j0O%M Igy7Pg(mQA6%T^t6vnx{nJzG:UG(w:SQnM1'Gc#{p.3e7WrYHmN>=|}kf|%3iw \T?|,DF*$Lp3G4orBOXqa2;U:T8Y#yvgfUYBC#T|.6_yCZrxu3 $ax=(K/\m"wt@7+FE#{W[}Ar,~Hn 0000004836 00000 n In the manufacture of pharmaceuticals, encapsulation refers to a range of techniques used to enclose medicines in a relatively stable shell known as capsule, allowing them to, for example, be taken orally or be used as suppositories. uuid:25f3e12c-faa7-4842-8246-dfb01902f2e4 Yq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXY 0000011141 00000 n endstream endobj 65 0 obj <>]>> endobj 67 0 obj <> endobj 66 0 obj <> endobj 68 0 obj <> endobj 69 0 obj <> endobj 45 0 obj <>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/Thumb 279 0 R/Type/Page>> endobj 48 0 obj <>/Resources<>/Font<>/ProcSet[/PDF/Text]/Properties<>>>/Rotate 0/Thumb 284 0 R/TrimBox[0.0 0.0 612.0 792.0]/Type/Page>> endobj 280 0 obj <>stream sf@&=N"R,Sn@v1pWttEd6qcwCy$4:cg 6Y(3]9soBEbeR xT C  endstream endobj 150 0 obj [ /PDF /Text /ImageB ] endobj 151 0 obj 5701 endobj 152 0 obj << /Type /XObject /Subtype /Image /Name /Im1 /Filter /CCITTFaxDecode /Width 2540 /Height 3309 /BitsPerComponent 1 /ColorSpace /DeviceGray /Length 151 0 R /DecodeParms << /K -1 /Columns 2540 >> >> stream trailer << /Size 272 /Info 235 0 R /Root 238 0 R /Prev 383912 /ID[<8f524b64cb19790b56639c121d46049d><30c4e58bc962789701ba09c4905ea561>] >> startxref 0 %%EOF 238 0 obj << /Type /Catalog /Pages 232 0 R /Outlines 184 0 R /PageMode /UseThumbs /OpenAction 239 0 R /Metadata 236 0 R >> endobj 239 0 obj << /S /GoTo /D [ 240 0 R /Fit ] >> endobj 270 0 obj << /S 508 /T 649 /O 725 /Filter /FlateDecode /Length 271 0 R >> stream According to the results of this study, the ideal tablet is small and white, strongly arched circular and coated, if the amount of drug requires a bigger tablet, the preferred fomat is oblong or oval with a coating. The aim of this review is to systemically survey published literature on the HPMC use in capsule shells and resolve questions regarding their suitability as a replacement for hard gelatin capsules. HWn\7-%zm6-+2@Ex[M'dWx1>$EQ!=br-u09>EwvkL.^7ft\q]`}o0>$SSx]K.eboJmsvg {vW?";DnG1:^ooqu`+?wlYBR(z.5x8qgxw|9uo% <>zW?al#K)Uz$d_5RAE9yj(?t5?E}9;D|u\J}RY)t< $L=U^%>~`vT NVG+$];rDgNv \LW=1DHhQ;>\uX9xF[^AOz(0W,yB4E@ 2A%^%#z 9N(g,L^We5kjDn4WATZ"E7-GrhX37R'8U I{%haa. 5\\2'[; UtHhMxZi8CRygvElQzRTkqKyY3PCNUQnk6OzNhdUZHTD0uIIJoMJChgZhJRFRqS0VtNVKBry4/PE Hb`````d32 8$ycE}L:Al[I"A bN(f`ee](i |z* endstream endobj 154 0 obj 109 endobj 144 0 obj << /Type /Page /MediaBox [ 0 0 610 795 ] /Parent 140 0 R /Resources << /XObject << /Im1 152 0 R >> /ProcSet 150 0 R >> /Contents 145 0 R /CropBox [ 0 0 610 795 ] /Rotate 0 >> endobj 145 0 obj [ 147 0 R 149 0 R ] endobj 146 0 obj 42 endobj 147 0 obj << /Length 146 0 R /Filter /FlateDecode >> stream %PDF-1.3 % 0000001189 00000 n XYq7FXYq7FXYq7FXYq7FXYq7FXYq7FX/2Q== HelveticaNeue-Roman.otf 0000005877 00000 n Injection Molding and its application to drug delivery. 4 0 obj HWYsF~]%t"9RI,ACAbziNmRq;owbrr>;'l:y,w31x6ad4d&&}2c#>e'o6oO.m&I&v}C7.n~*Cn']xH>yq'w^{,8S)1$HpEX XMcod=SlD0|u}x`unOr|w]c] L=|Oa)>II2;\kSS>B|E1[jSNc!IE:i@=q}]e GEIe>`aPlc5/o&39Zebgp %["iMalC]yU6{[M *N#0P.0pL`,=K3BeOOfW^1m'`;fM@L 3 endstream endobj 271 0 obj 619 endobj 240 0 obj << /Type /Page /Parent 231 0 R /Resources 241 0 R /Contents [ 250 0 R 252 0 R 254 0 R 256 0 R 258 0 R 260 0 R 262 0 R 269 0 R ] /MediaBox [ 0 0 595 842 ] /CropBox [ 0 0 595 842 ] /Rotate 0 /Thumb 185 0 R >> endobj 241 0 obj << /ProcSet [ /PDF /Text ] /Font << /F2 245 0 R /F4 246 0 R /F5 247 0 R >> /ExtGState << /GS1 264 0 R /GS2 265 0 R >> /ColorSpace << /Cs5 248 0 R >> >> endobj 242 0 obj << /Type /FontDescriptor /Ascent 714 /CapHeight 714 /Descent -191 /Flags 96 /FontBBox [ -165 -214 1099 951 ] /FontName /HelveticaNeue-LightItalic /ItalicAngle -12 /StemV 63 /XHeight 516 /FontFile3 268 0 R >> endobj 243 0 obj << /Type /FontDescriptor /Ascent 714 /CapHeight 714 /Descent -191 /Flags 32 /FontBBox [ -166 -214 1050 967 ] /FontName /HelveticaNeue-Light /ItalicAngle 0 /StemV 63 /XHeight 516 /FontFile3 267 0 R >> endobj 244 0 obj << /Type /FontDescriptor /Ascent 714 /CapHeight 714 /Descent -202 /Flags 32 /FontBBox [ -165 -220 1162 950 ] /FontName /HelveticaNeue-ThinExt /ItalicAngle 0 /StemV 46 /XHeight 512 /FontFile3 266 0 R >> endobj 245 0 obj << /Type /Font /Subtype /Type1 /FirstChar 32 /LastChar 240 /Widths [ 222 258 352 648 648 926 741 222 296 296 408 600 222 407 222 407 648 426 648 648 648 648 648 593 648 648 222 222 600 600 600 630 800 686 722 796 759 648 593 833 759 166 537 704 574 962 759 816 667 816 704 667 592 740 668 1018 648 668 611 296 407 296 600 500 166 593 630 611 630 611 296 648 611 166 166 556 166 964 611 630 630 630 352 537 315 611 556 870 537 519 519 296 222 296 600 222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648 648 0 0 0 0 0 800 0 0 0 222 0 0 222 600 222 222 0 611 222 222 222 222 222 0 0 222 0 0 0 0 0 222 0 222 222 0 0 0 222 0 0 0 0 0 500 0 0 0 0 0 0 222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222 ] /Encoding /MacRomanEncoding /BaseFont /HelveticaNeue-ThinExt /FontDescriptor 244 0 R >> endobj 246 0 obj << /Type /Font /Subtype /Type1 /FirstChar 32 /LastChar 240 /Widths [ 278 241 370 556 556 889 611 278 241 241 352 600 278 370 278 333 556 556 556 556 556 556 556 556 556 556 278 278 600 600 600 537 800 630 667 704 685 593 537 741 704 222 500 648 537 833 704 741 630 741 667 630 556 685 593 907 574 611 574 241 333 241 600 500 185 519 574 519 574 519 259 556 537 185 185 500 185 833 537 556 574 574 315 481 296 537 463 741 481 463 463 333 222 333 600 278 0 0 0 0 0 0 685 0 0 0 519 0 0 519 519 519 0 0 0 0 0 0 0 0 0 0 556 0 0 0 0 537 0 400 556 556 0 500 0 537 800 800 990 0 0 278 0 0 278 600 278 278 0 537 278 278 278 278 278 0 0 278 0 556 0 0 0 278 0 278 278 0 0 0 278 0 0 0 0 0 500 1000 370 370 278 278 0 278 0 0 0 0 0 0 444 444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278 ] /Encoding /MacRomanEncoding /BaseFont /HelveticaNeue-Light /FontDescriptor 243 0 R >> endobj 247 0 obj << /Type /Font /Subtype /Type1 /FirstChar 32 /LastChar 240 /Widths [ 278 278 370 556 556 833 611 278 259 259 352 600 278 370 278 333 556 556 556 556 556 556 556 556 556 556 278 278 600 600 600 537 800 630 667 704 685 574 537 741 704 222 500 648 537 852 704 741 630 741 648 630 556 704 593 907 574 574 574 241 333 241 600 500 185 519 574 519 574 519 259 556 537 185 185 463 185 833 537 556 574 574 315 481 296 537 463 741 463 463 426 333 222 333 600 278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400 556 556 0 0 0 0 0 800 990 0 0 278 0 0 278 600 278 278 0 537 278 278 278 278 278 0 0 278 0 0 0 0 0 278 0 278 278 0 0 0 278 0 0 0 0 0 0 0 0 0 0 0 0 278 0 0 0 0 0 0 444 444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278 ] /Encoding /MacRomanEncoding /BaseFont /HelveticaNeue-LightItalic /FontDescriptor 242 0 R >> endobj 248 0 obj [ /CalRGB << /WhitePoint [ 0.9505 1 1.089 ] /Gamma [ 2.22221 2.22221 2.22221 ] /Matrix [ 0.4124 0.2126 0.0193 0.3576 0.71519 0.1192 0.1805 0.0722 0.9505 ] >> ] endobj 249 0 obj 1766 endobj 250 0 obj << /Filter /FlateDecode /Length 249 0 R >> stream 001.102 0000009409 00000 n ($;,WA0y(dMdP*_Z !J!dN#U5o2 stream 0000001245 00000 n Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 0000038865 00000 n 0000001269 00000 n 0000014057 00000 n CbL!DDDDH`DDDZB+1n-|(-lL;2yZL"CdT9pP5My tC ~ "p] D!P*2ahA$s7C=%9N P:d\6 h:N|4I]OI}I{=OOO{V>a$oV?_oJ]ZPzmKaXjKwe aO0 B Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. Development of a new engineering-based capsule for human drug absorption studies. 2020-09-14T10:29:27+05:30 FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7F /wkz 0+PzhJSktMTU5PRldYWVpbXF1eX1RlZmdoaWprbG1ub2R1dnd4eXp7fH1+f3OEhYaHiImKi4yNjo 0000011164 00000 n 4 0 obj JPEG ;K ;_jgb[}}9Urk("u}{ww}uj& '\8=j0 h7~\w[Tej]i9y;;`mOonU+)7|_YcG Zv}z~O ]lpPWw+A-m"Dg]q\ G-6 "(O`at.^@Rgv|'Pd2Ix{ bncl,.-.e|&Y`kX. k'%}2jHBI]C(na]8)< H@_xHXp* dMtm~!YsG4W??d1 m+)L#/D})pF2!RXdt_)oZI&?n+7_ H[~LD+\c[u}&&MeoI!\/h)K`b@OH >AyfIwu%,Av6\F0a8(Tutx>N>qr>~O-UYVEp>ps4yW=~"o_~Y:FPD&7u&KmUojVGC FKj,iK"XH[+A"q';T7~t Xnj I fV io 3J?k[4RU*U(1"~ OnHGdwNMdda4=+Xl5 XYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FX endobj AAIRAQMRAf/EAaIAAAAHAQEBAQEAAAAAAAAAAAQFAwIGAQAHCAkKCwEAAgIDAQEBAQEAAAAAAAAA 0000001423 00000 n endobj Different types of advancement involved in different types of dosage forms like adhesive tablets, gels, ointments, patches, fast dissolving tablet, mouth dissolving tablets, or dispersive tablets etc are summarized. FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7F q7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq hm-q/~5I xWHd8$I;[h/bDLzL=&A)#,TQIvz{LH9p"W`MI,{n@UC;mq,+R\rv$VHFt8]8WnpB%y=@"EvC}fZp;uS*7 5W@g@A"+7?O$EU"! 7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7 1OT0ZXWFlaW1xdXl9WZ2hpamtsbW5vY3R1dnd4eXp7fH1+f3OEhYaHiImKi4yNjo+Ck5SVlpeYmZ +DlJWWl5iZmpucnZ6fkqOkpaanqKmqq6ytrq+v/aAAwDAQACEQMRAD8A9U4q7FXYq7FXYq7FXYq7 obHwFMHR4SNCFVJicvEzJDRDghaSUyWiY7LCB3PSNeJEgxdUkwgJChgZJjZFGidkdFU38qOzwygp lm{!Y)a>7t 0000012571 00000 n swb_wsxs{x|8e? {SGW3pd^%be@4]=Oa4> Rkl0%no\` Inches 0 XYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FX Journal of controlled release : official journal of the Controlled Release Society, Pharmaceutical science & technology today, By clicking accept or continuing to use the site, you agree to the terms outlined in our. Mvy"uL23Ns2}_#4wPR7 p&,DnQ=B/ozg!o,C` 0000000864 00000 n 0000050257 00000 n 0000015704 00000 n 7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7 NOVEL ORAL DELIVERY OF IBUPROFEN SOLUTION IN HARD GELATIN CAPSULES, Cosmetic, Biomedical and Pharmaceutical Applications of Fish Gelatin/Hydrolysates, DUOCAP: THE CAPSULE IN CAPSULE TECHNOLOGY, Investigation of Mixing Time on Carrageenan-Cellulose Nanocrystals (CNC) Hard Capsule for Drug Delivery Carrier. [BQ+$hgPC1eL=-e(v!AFG0 0000007769 00000 n 0000001147 00000 n 0000000611 00000 n 2007-10-10T09:39:50Z 0000001381 00000 n U \t <> comparison to gelatin based capsule. 8.500000 The developed capsule is a unit dose of liquid containing solubilized ibuprofen delivering the drug directly into the gastrointestinal tract (GIT) with higher patient compliance and ease in manufacturing. fk02CPQ4X[t@YX5-e=GAqhU o Bh}jJ[ LiBKU>Nb*N]{Z'*W}+\?$[fA+*MhV:+5'jV\H^^QLF=~1gMFb-K3X)OhJ5242qN2[k])CtNP@@[C |. XYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FX 11.000000 aL n;|,>m 7wzW;NvIm H;On~VtomIovoVwIWouo}'wmS/]_m'I>WO_$oTozCu_=|{N_&[{[Zmi'mmk~}_o}Vo^+&;M{}]o^U_vk{z_oZ__it=K_Jo],'K]oKe=(_n`G/xIo/)/n_5G}} Cz}H.$_b~5Vk{jK}.Tz; wCK}z v;o5"b?H_on}{Nvi&]m/dQk{?M_tm^zO[i[]UuowzN~z[~oUKonnJWoZ{t[km-Uvm'_tm-JKzjkI^z}m%i7O}i-JavnI6 --VVjVh+L\'`6N$ >MN0`l0MM0ACfl "d0@Q 5A|>B k#40@8"x498mC`530ha`3`"[&C&8a0 t$TP+0A_0%~ The gelatin capsule was invented early in the 19th century as a result of the need to mask the obnoxious taste of many medicinal substances such as oleoresin of copaiba, which is extremely nauseating when taken by mouth. YR@76Fb%-C!4G30 l [9JX4G CPTHmMKr8#tIpBTBY32 yb*iiG!B6l;H=X0HK!RGd! !,6M&m`tD!y6noD7B":Gu 2020-09-14T10:29:27+05:30 0000028340 00000 n 0000001987 00000 n 0000009432 00000 n ".!EZAzkWzUW^kz]%V}ik^KZZ.jC6Dzz%uik_u.";k_Z_~]U:]u++VTs:__*k[ZtW/"{UtUozR['ZmWZm?kz[*_voT:Uv_a.IBP =$]Twida4 6I1 =` `( lR`0AxBU4Baa&h mZjdQjK Uh_Dj""$&!\m4"""1 cZe*TKLP0JA+BA0U`D%BkiAIiZUM+zkjoVA-6jOWuou_K_YgKT=.>K.z}YP teaj._3=/Potp._K-"IoAi}R[{^%% Wax"X ]%U.UU a)i0KAEE @Zl$EhAH*/-J#*v~?Q]GM}+2UTr)|[/jSY$uZ)n1^_n7 G-KToQ2ddb,YFwA l0:g3@sFD34G[2NU$0"4c> gIB(L54"@@dP@\DD6 3`j4St SJ(N# %PDF-1.5 "[!nDq5@Ov"II|5UZhD$ *`{a~'~nz-zM}?Wv51vZ .i0j[NohpaUw[_{}Oo EvKt;]wrV]{+~;OX!GB=]]V6gEt~^=jiu~ ~ oWo":m (hJD!Vj~v5q h,&>BQWl^%'o&}Muu>QCs]W/ER(S52}Ijx dz#CE.~CU.c9Q %PDF-1.5 % x=k6]o'myhALmjb;YgrAJgFco_?$ )wWuHF/ G7_n6G\o6OGfu}q'WEq*BeJ fM]|zPbk_=(]U!RH*_P.9oE)@'-+FgA|{s~|}2?j_'zi};73x!gzvs9WqWAS8/!Ei)MaT A$v ;@I L"!va2M$v;OztzpIo~wz[H?o[oto7o_cm/-UvwoKo]_JW.z_O}%sut:]w]]wJm}ZWKz|}[KuXcN=wK1?i|?Vvu~uX}z_woI?>[~|?k/&U>=]ub? K v}o[Y{|*.{mY/OR?}Co'tfcmZ}{ ;;o|w7{iuoo{VE`_ {~ x?i-n[GW7O?KvnW\R~wu_^WMwn~ozUt^}i/tzm/iwal%:^v+Wia4L%aM BtNAa3gP!P"30hAF[a@!p a#X5 %< $v Pchf wPTM*! q7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq QuarkXPress(tm) 6.1 0000015727 00000 n <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/Annots[ 11 0 R 12 0 R] /MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> 7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7 0000002634 00000 n stream P1t618MVTfFXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7F The first patent was granted on 25th March 1834 for soft gelatin capsule to Mr. Franois Achille Barnabe Mothes, a French pharmacy student. FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7F 0000017409 00000 n qbnJ2en5KjpKWmp6ipqqusra6voRAAICAQIDBQUEBQYECAMDbQEAAhEDBCESMUEFURNhIgZxgZEy % trailer << /Size 155 /Info 138 0 R /Root 143 0 R /Prev 606166 /ID[<64e5a8dd9737c3d4e3844bcad7c2b0eb><64e5a8dd9737c3d4e3844bcad7c2b0eb>] >> startxref 0 %%EOF 143 0 obj << /Type /Catalog /Pages 137 0 R >> endobj 153 0 obj << /S 119 /Filter /FlateDecode /Length 154 0 R >> stream 0000002396 00000 n 0n=ZA dU$AA L'pd2* 2epdABpD*-82&C=P d6AA!*d4Uu. t0B"Aa8zaUOB!#SY$eP&]\RQ&B)xL!359ZL%Ug|R.GbmBw-p,& -2$ :e=1LDB!*KPaPvk(C8Gz$j4pm$Ia:OKt} vGA68V>H*}br!y. Aqlp!EbOz)&^H6cM}9p>L^}~Q^'ta`n.]rf{Jvu&X??roVv)Z8Rows8z^SM!ATGogsh"=R]7+-$,8O4 4b`{^D2=A}viB=xn;Ean/JrWxp*v@G ?E _;$^@}q^@BpQiiq-Rx$YB&Ba P Present global market demands for plant based capsule to replace the animal based product. c;xtP.&}_ooWW]!NLi}Wnd-zO uknW;_m-^Km+ -[,4[aV&x4Z@i D pa80HAblq"6 4XUaiAQut0t\5uDDDDb#ZGg54VHn+H&920A!c$q26pDAD a!Ra !uiEL!j8` dS@`=K4u4z.C0 0@NVm0A"i&aPiA9}7AM7MV6;Zoz&}w:}]WuJ}/UKzWV[_VUK*ZRu__TXT1OkJR-v_j8ZIu/UO_IzHXZIz:KAqKu>Z^/]V_Z]}$NUj^Zt%U^ZTKzoJu`$ ]V Uu. !5]HBK.^(J$/Zu \uKd?!! Constipation is a gastrointestinal tract condition that can lead to abnormal stools, uncomfortable storage and passing with pain and stiffness and treatment need to medication and also surgical treatment is also available for treating constipation. Open Type 3 0 obj FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7F 0000001446 00000 n ]n.*_&C=n@iP! 5wxCkr#0Yn}`{~kjMx;Xr(5b?.$oR$Cd[G@'/AL%dH?Ca O @'0wX81'kW-;4h#2Eo *^`fXSnkYQV:%g 6]]*cJ:ym`{X{T}2[hF ^Bm0?A2:-gVz08 \T-$syi>bQVW1[Y^@wz&%Pn^n-?RxWI 'VI*jm]\P{>,4Xn:". 0000001087 00000 n HelveticaNeue-Roman Results of the study showed that pin setting was critical for controlling the fill weight and the weight variation of capsules produced on the In-Cap, and appropriate selection of pin settings and bed height can reduce the weight variability seen, especially with poorly flowing high-dose formulations. %%EndComments endobj 0000005900 00000 n Hx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8f/8AAEQgA/AEAAwER 73 0 obj <><><>]/ON[137 0 R 277 0 R]/Order 278 0 R/RBGroups[]>>/OCGs[137 0 R 277 0 R]>>/PageLabels 65 0 R/Pages 67 0 R/Type/Catalog>> endobj 132 0 obj <>/Font<>>>/Fields[]>> endobj 71 0 obj <>stream 3 0 obj 0000017589 00000 n Yq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXY True This review is comprehensive, specific to fish gelatin/hydrolysate and cites recent research, finding that fish gelatin is immunologically safe, protects from the possibility of transmission of bovine spongiform encephalopathy and foot and mouth diseases, has an economic and environmental benefits, and may be suitable for those that practice religious-based food restrictions. 0000003947 00000 n 142 0 obj << /Linearized 1 /O 144 /H [ 668 218 ] /L 609136 /E 7577 /N 18 /T 606177 >> endobj xref 142 13 0000000016 00000 n ,4ebkkk*t TMLBmM==:1&46RNP*kiiO!.m%0AN$ &;a+%iRCt0()B"" @hvvM=#MSNHa q7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq The information available on the physical and chemical instabilities of excipients and their incompatibilities with the active pharmaceutical ingredient in solid oral dosage forms, during various drug-manufacturing processes is reviewed. 0000001126 00000 n <>/Font<>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 595.44 841.68] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>>

Sitemap 0