Whilst the perceivable dangers of LLLT are mainly related to retinal damage (both clinician and patient) and skin burn (mainly related to shorter UV wavelengths), the safety of LLLT is well documented in a number of standards such as US Code of Federal Regulations, American National Standards Institute and the International Standards Manual, and other laser safety books and review articles [21, 22]. Phototherapy with light emitting diodes: treating a broad range of medical and aesthetic conditions in dermatology. Gupta, A., Dai, T., & Hamblin, M. R. (2014). Calderhead, R. G., & Vasily, D. B. Lightemitting diodes in dermatology: A systematic review of randomized controlled trials. Downsides of this is it uses a bunch of wavelengths that have little to no evidence to support them and it doesnt have NIR. The internal temperature may be the same, but the skin of the turkey will be charred in the 800 degree oven). 1-36). Non-invasive peri-orbital rejuvenation: Radiofrequency dual radiowave energy source (rf) and light emission diode system (LED). Note: You dont want to know the joule (J), you want to know the J/cm2. But assuming they dont then this would be a slightly larger flexible mask, which might be appealing to people that found the other flexible masks as being slightly too small (I have heard that from only a couple people, but usually it is with respect to the height and not the width). This is new and I couldnt find it for sale on its main website, but I found it here: I would pass on this one because the Omnilux Contour and FaceLITE are identical but cheaper. Major downside right off the bat is that it uses a blue wavelength that isnt the one that has been found to help with acne (415nm) but has been found to induce hyperpigmentation. Although a more recent in vitro study by Chen at el (2018) offers very preliminary evidence that LLLT with yellow light at 585nm can help reduce pigmentation. I tried to include the most popular masks and any masks that I could find information on in the FDA 510(k) database. But turns out that isnt the case! But it doesnt make Light Salon any better than any of the other flexible masks that I cover in this post. This one has a lot of unnecessary wavelengths (personally, I would Just use the 630nm setting on this) and it has some wavelengths (439, 450-460nm) I would actively avoid using. Their fluence is 18 J/cm2. (2006). This one is available LOTS of places. Also, while it only recommends 8 min sessions, the frequency is 7 days a week (I prefer the masks that can make a recommendation for fewer days a week given the irradiance). Barolet, D., Roberge, C. J., Auger, F. A., Boucher, A., & Germain, L. (2009). This and the DDG LED mask are the most popular in terms of LED masks that you see on Instagram, probably because it has been gifted to a number of bloggers/influencers (I was one of them) so it has gotten more exposure. The big downside is that when you use the Red/NIR setting, there are no light coverage on the chin at all (there is only light coverage on the chin with the blue + red setting). Lask, G., Fournier, N., Trelles, M., Elman, M., Scheflan, M., Slatkine, M., & Harth, Y. So in my mind, I set 50 mW/cm2 as the upper threshold, because any higher and the mask could be uncomfortable to wear. Exact action spectra for cellular responses relevant to phototherapy. Regulation of skin collagen metabolism in vitro using a pulsed 660 nm LED light source: clinical correlation with a single-blinded study. Lowlevel laser therapy for closedhead traumatic brain injury in mice: effect of different wavelengths. Not sure how long that will last. But the same research that applies to face masks applies to those devices, so you are able to assess their potential efficacy using the parameters above. Even within different studies on the same animal models, there can be contradictory findings. But the downside of this one is the price and only 1 year warranty. High enough irradiance so that the recommended usage isnt 7 days a week and ideally less than 10 minutes. Gupta et al (2014) carried out a similar comparison on wound healing in mice and again found that 660- and 810-nm lasers were effective, while a 730-nm laser was not effective. All in all, this one just doesnt seem like a great option, especially since there are more affordable ones with better key parameters. On that note, I-smart marketing LTD submitted a 5, Transparency from the company as to what the irradiance is (and the. And 415nm appears to be best and many recommend using it in combination with red or NIR (but blue +red has more evidence). Current Status of Light-Emitting Diode Phototherapy in Dermatological Practice. Some of the limited studies using yellow light were not able to be replicated by different researchers. Ultrastructural observations of human skin following irradiation with visible red light-emitting diodes (LEDs): a preliminary in vivo report. This mask uses red and NIR and discloses the irradiance, so those are two positives. So it is best to draw guidance from clinical studies only (later I provide an overview of some clinical studies focused on skin rejuvenation). First, while it does have, If you are ok with uncertainty and not knowing the irradiance and having to use it for 20 min instead of 10, this isnt a bad option because at least it uses good wavelengths. Three wavelengths of light that have demonstrated several therapeutic applications are. Calderhead, R. G. (2018). (Calderhead & Vasily 2016). Serrage, H., Heiskanen, V., Palin, W. M., Cooper, P. R., Milward, M. R., Hadis, M., & Hamblin, M. R. (2019). Wu et al (2012) used a 730-nm laser on TBI in mice and found it to be ineffective while 660 and 810 nm lasers were effective. Comparison of the low level laser therapy effects on cultured human gingival fibroblasts proliferation using different irradiance and same fluence. Wavelengths shorter than 600nm tend to scatter, rather than to penetrate deeply into the body tissues. There is no fixed value of fluence that always produces a positive LLLT effect. This has good wavelengths and irradiance, but it is super expensive. As a quick reminder, there are 7 flexible LED masks made by the same manufacturer & have the same key parameters but they have some small differences in design elements (& variations in price). Medical Research Archives, 6(1). In order for LED masks to actually be effective, the wavelength and irradiance are key. Clinics in Plastic Surgery, 43(3), 541-550. Therefore, it offers very little to dermal renewal and repair. Karu, T. I. (2010). The price has also been changed to $299. Lasers in medical science,29(1), 257-265. Gavish, L., & Houreld, N. N. (2019). (2013) Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. 2013 Mar;32(1):41-52. Its interesting that the irradiance of this is SO different front the Dermashine because I was wondering if all of these look alike masks would have the same irradiance (and were just the same mask, rebranded). Also, having only a 1 year warranty is a downside. The optimal clinical irradiance is considered to be around 40150 mW/cm2 (Calderhead, 2018; Sorbellini et al., 2018). (2008). If the medicine is incorrect, i.e., an irradiance which is too low (resulting in no effect) or too high (resulting in photothermal damage), no amount of playing around with the dose will achieve the optimum result. Migliardi, R., Tofani, F., & Donati, L. (2009). Journal of Cosmetic Dermatology,19(9), 2288-2294. Finally, the company doesnt provide information about the irradiance (power)and if the mask isnt appropriately powered, then the wavelengths arent going to reach their destination in the skin. Journal of the European Academy of Dermatology and Venereology, 25(1), 49-58. The light energy helps to enhance our cellular potential (helping our cells to function more efficiently), promote oxygen utilization within the cell, and generate cellular fuel (or ATP) (Barolet, 2018; de Freitas & Hamblin, 2016; Hamblin, 2016). If LED therapy is administered several times prior to a UV insult, a mechanical trauma such as a CO2 laser treatment or a surgery, one may prevent undesirable consequences such as sunburn, postinflammatory hyperpigmentation (PIH), or hypertrophic scarring, respectively. Barolet goes on to talk about those applications, ocular symptoms (typically with blue light), discontinue sessions if any side effects occur, Many companies cite evidence from in vitro or animal studies. Also, you have to wear it for 30 min 7 days a week (bc the irradiance is so so low) and there is only a 1 year warranty. The main benefits seen in clinical trials of LLLT for skin rejuvenation (in other words, excluding research focused specifically on inflammation) are: Biopsies have shown increased collagen and elastin production that would account for many of these benefits. The Qure mask has the same wavelengths, shape, and nearly identical irradiance as the DDG Spectralite and it has an app that goes with it. Photomedicine and laser surgery, 22(3), 241-247. Prospective randomized study on the efficacy of blue light in the treatment of psoriasis vulgaris. IUBMB life,62(8), 607-610. Mainly the price and the 1 year warranty are some downsides. ~530 nm (green): it might have some benefit for pigmented epidermal conditions and superficial skin conditions like stretch marks but its use for these conditions has not been proven yet (De Cordova, 2021). A. The clinical and histological effect of homeuse, combination bluered LED phototherapy for mildtomoderate acne vulgaris in Korean patients: a doubleblind, randomized controlled trial. Medical Laser Application, 21(3), 165-175. The wavelengths and the irradiance for each wavelength are as follows (note that you cant just add up the irradiance for each wavelength to get the total irradiancethe only time the irradiance is additive is when the wavelengths are sharing a double chipinstead I would say that that red setting ranges from 11-40 mW/cm2) and the red+ blue setting ranges from 40-60: 415nm (60 mW/cm2); 605nm (26 mW/cm2); 630nm (26 mW/cm2); 660nm (40 mW/cm2); 880nm (11 mW/cm2). Low level light therapy with light-emitting diodes for the aging face. Fluence or Energy Density- The Recommended Dose, FLUENCE = (IRRADIANCE x .001) x TREATMENT TIME IN SECONDS. If the device has an imprecise wavelength, then that means you arent getting as pure or high quality a light. AlmeidaLopes, L., Rigau, J., Amaro Zngaro, R., GuidugliNeto, J., & Marques Jaeger, M. M. (2001). Note: some of the links below are affiliate links where I will earn a commission from your purchase. Journal of the European Academy of Dermatology and Venereology,26(2), 219-225. Evidence has been also reported indicating the higher efficacy of the combination of different wavelengths in LED therapy than monotherapy (Opel et al., 2015; Jagdeo et al 2018). Lasers in medical science,35(2), 307-316. For example, Light Salon recommends 10 min sessions. The term blue light can refer to a relatively wide range of wavelengths from violet (390425 nm), indigo (425450 nm), royal blue (450475 nm), blue green (475500 nm)and they have had very different results. Lasers in medical science, 20(1), 6-10. Another major downside is that it doesnt include NIR. Ablon, G. (2018). The company is leaders in LED research (and for what its worth they are nice and always helpful). Omnilux and FaceLite are almost identical except they differ in terms of the, Here is where it gets complicated and super nuancedOf the 7 masks that are all made by the same manufacturer, the manufacturer told me that all 7 have the exact same wavelengths and irradiance. Calderhead RG. The only difference is it is missing the strap for the top of the head and it is, Then for other territories, pricing varies a bit depending on where you are so Current Body gave me a code to just give people. Zheng C., Rajabi-Estarabadi A., Hirsch M.M., Nouri K. (2020) Light Emitting Diodes and Low Level Laser Light Therapy. Karu, T. I. Wearing eye protection with blue light is strongly recommended. Under the spotlight: mechanisms of photobiomodulation concentrating on blue and green light. So it could make it easier to find a good deal (or at least see which store has the best Rakuten cash back). The dark art of light measurement: accurate radiometry for low-level light therapy. a 4 month update can be found in my Omnilux Story highlights! I believe the company is based in Australia, so for those in the US, the shipping will be $19.95. Lasers in surgery and medicine,44(3), 218-226. Lasers in surgery and medicine, 50(6), 613-628. One thing to keep in mind is that the irradiance and fluence used in vitro studies are often different from those used in clinical studies. At higher doses (e.g., 50 J/cm2 ) and after 24- hour exposure, it was shown that cellular viability was significantly reduced to 74%, leading to a significant increase of cellular injury to 365% of the control.. I was happy to see this had a good irradiance and used Red and NIR in the right wavelengths (and that the company disclosed it but that was, 2 year warranty (BUTbe sure to register your device within ONE MONTH of buying it or the warranty is void. You can find this in both Shape A or Shape B. Not saying I recommend this mask, but if you do check it out, you can save 25% at. Light stimulus will be insufficient to trigger a cellular function if it is delivered below the recommended dose and will inhibit activation of these responses if a dose higher than indicated is delivered. Because these products only work if you use them). Therefore, LED light therapy aids skin rejuvenation through increasing collagen production and decreasing collagen degradation (which can be seen with the tightening of lax skin and the reduction of wrinkles). It is not that the device wont be effective, it is just that you really wont be able to gauge whether it is comparable to masks that have been found to be effective. Trelles and Allones (2006) found applying red light (633nm; 80mw/cm2; 96j/cm2) after laser resurfacing cut healing time in half. But you could get this and just use the red 630nm setting (though red + NIR is more effective). Photobiomodulation via multiple-wavelength radiations. However, if you live in the US, because of the exchange rate (they are based in the UK), this one may end up being pricier than some of the other ones that are identical to it (i.e., CurrentBody, PRIORI). Avci P, et al. Consulting Room 2020;3(03):1315. This is why you really want to find out the irradiance before buying! T. Nakanishi-Ueda, H.J. The nuts and bolts of low-level laser (light) therapy. Red light can help this process because it stimulates collagen synthesis and fibroblast formation, anti-inflammatory action, energy production in mitochondria, and DNA repair (Barolet, 2018; de Freitas & Hamblin, 2016; Hamblin, 2016). Photochemistry and photobiology, 84(5), 1091-1099. Calderhead, R. G., & Omi, T. (2014). Skin rejuvenation is strongly linked to the wound healing process. International journal of cosmetic science,38(4), 325-345. This includes The Guidelines for Skin Exposure to Light in the International Standards Manual (IEC-825) which states that an exposure of less than 200 mW/cm2 is safe, and the marketing and the use of therapeutic LLLT is approved by the Food and Drug Administration. So thats a big lesson to not assume two masks would have the same irradiance if they have the same wavelengths, number of lights, and look identical. If the goal is overall skin rejuvenation (including reducing inflammation and speeding up healing), choose a mask with NIR (ideally 830) as the literature has consistently found that this wavelength targets a larger number of the necessary cell types and has a better effect on the overall skin rejuvenation process than other wavelengths (Kim & Calderhead, 2011). A single-blinded randomised controlled study to determine the efficacy of Omnilux Revive facial treatment in skin rejuvenation. Wu, Q., Xuan, W., Ando, T., Xu, T., Huang, L., Huang, Y. Y., & Hamblin, M. R. (2012). Sawhney, M. K., & Hamblin, M. R. (2016). (Mechanism of Action), Things to keep in mind (including notes about blue wavelengths), Some IG posts Ive done on the LED use, results Ive seen, and. Among clinical studies focused on skin rejuvenation, irradiance values ranges from 6 mW/cm2 to 150 mW/cm2, with the median being 55 mW/cm2. But I guess one bonus is that they provide some white paper results (which should be taken with a grain of salt but they are better than nothing.). Low level light therapy with light emitting diodes. Calderhead, R. G., Kim, W. S., Ohshiro, T., Trelles, M. A., & Vasily, D. (2015). I produce this content for free, but if you found this helpful & would like to support my work, I would appreciate if you shop through my links or use my affiliate discount codes. In Lasers in Dermatology and Medicine (pp. Out of the flexible LED mask options I would pick Omnilux because it is the most affordable (after coupon code) out of the Shape A masks and for all the other reasons I outlined above. It is the power density of a beam that will determine more than anything else (apart from wavelength) the magnitude of the bioeffect in the target tissue (Calderhead, 2018). Where did you see that it was 880nm? 1 year warranty [again, this is surprising given the price I would expect 2 year warranty]. Res. (2007a). Identical to Light Salon and Current Body. Also, one nice thing about the Qure is that it has an app where you can just use the blue+red light on one portion of your face. 415nm has been found to be beneficial for the treatment of acne (inflammatory lesions respond better to blue light than noninflamatory lesions like whiteheads and blackheads). A systematic review of at home devices used for nonesthetic purposes (e.g., wound healing, scars, pain, and cognitive function) found that devices finding significant results had irradiances ranging from 8-50 mW/cm2 (Gavish & Houreld, 2019). Lasers in Surgery and Medicine: The Official Journal of the American Society for Laser Medicine and Surgery, 29(2), 179-184. Bonus: Because this is sold at a variety of places, you can often find it on sale. New addition to list as of 6/11/2021. Green light (490560nm) and white light (400670nm) did not affect the barrier recovery rate (Denda & Fuziwara, 2008). The best part about the DDG and Qure is that it is only 3 minutes. For example, the FaceLITE LED mask has LED arrays with a nominal wavelength of 633nm within the range of +- 10. Dermatol Surg. The main risks that have appeared in clinical trials were minor and self-resolving and include (Jagdeo et al., 2018). This one is the one I think I would choose if I went with a hard-sided mask because it has great wavelengths, one of the best irradiance, and it has a neck attachment. The higher the grade of the LED, the narrower the bandwidth of the emitted photons, allowing LEDs to emit the rated wavelength plus or minus a very few nanometers. (Calderhead & Vasily, 2016). It is $296 after you use the code VANESSA10. Sanclemente, G., Medina, L., Villa, J. F., Barrera, L. M., & Garcia, H. I. But a higher irradiance isnt always better. I have updated it with the new price. Caution must be emphasized especially for epileptic and photophobic patients especially if LEDs are pulsed. (Barolet, 2008). When that gap gets large that indicates low quality LED). That means that 90% of the photons are at the rated wavelength and will therefore optimally target wavelength-specific chromophores at that wavelength. In an animal study, Blue light (430510nm) delayed the barrier recovery, whereas red light (550670nm) accelerated it. Please let us know thanks!! Photobiomodulation in dermatology: harnessing light from visible to near infrared. This only has one strap across the back, so this might be one where you might want to buy an extra velcro strap to help you better customize your fit. Enwemeka, C. S., Parker, J. C., Dowdy, D. S., Harkness, E. E., Harkness, L. E., & Woodruff, L. D. (2004). Keep in mind that lower irradiance (<50mW/cm2) is less likely to induce skin hyperthermia (heat) leading to potential deleterious effects (Barolet et al 2016). Many LLLT devices have been commercialized without FDA or other medical regulatory approval because the light output is below a nominal hazard level. This next figure from Kim and Calderhead (2011) further illustrates the confirmed mechanisms of action for the three main endpoints of 830 nm LLLT (633 nm has beneficial effects as well), namely wound healing, the anti-inflammatory response through acceleration and quenching of the post-wound inflammatory phase and pain attenuation. (2016). Best results are not seen immediately post treatment, but later on at 4, 8 and 12 weeks or more. And its cheaper. Laser therapy,24(4), 277-289. Ok if you want to know even more about the mechanism of action, this section is for you! This is the most gimmicky LED maskapparently this one also has rose quartz crystals. enhancing cellular mitochondrial function and ATP production through interacting with a photoreceptor called cytochrome c oxidase. Photochemical & Photobiological Sciences,18(8), 1877-1909. Here are a few snippets: Some other interesting applications that still have very little research on them were outlined in Barolet (2008). One good sign was that it comes with eye protection (as it should since it uses blue wavelengths). This is the mask that I used from Nov. 2019-Dec. 2020. if proliferation is required, the cell will proliferate. In the red wavelength, this uses 620nm -750nm (thats a HUGE span not great at all. Therefore, if they dont share the data it would make me suspicious as to whether they know the irradiance or if there is some reason they dont want to share it. Hadis, M. A., Zainal, S. A., Holder, M. J., Carroll, J. D., Cooper, P. R., Milward, M. R., & Palin, W. M. (2016). Handbook of Lasers in Dermatology, 307327. Very expensive mask and the company is very guarded about the wavelengths and power. Low-Level Laser (Light) Therapy for Cosmetics and Dermatology. But I want to note that I appreciate how helpful and transparent the contact at Dermashine was nonetheless, I was shocked at how low the irradiance it (I actually thought it was a typo so I confirmed it was 0.5mw/cm2). Lasers in Medical Science, 33(7), 1431-1439. Optics & Laser Technology,135, 106698. Dermatologic Surgery, 43(3), 371-380. Clinical efficacy of self-applied blue light therapy for mild-to-moderate facial acne. I would pass on this one because the Omnilux Contour and FaceLITE are identical but cheaper. The utilization of nonthermal blue (405425 nm) and near infrared (850890 nm) light in aesthetic dermatology and surgerya multicenter study. Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice. It is quasi flexible, but it it wont lay flat on its own. Barolet, D. (2018). Also, you wont know what you are working with and you may be wasting your time and money using the device. Journal of Cosmetic and Laser Therapy, 11(2), 125-128. Photodynamic and photobiological effects of light-emitting diode (LED) therapy in dermatological disease: an update. A., Kellett, N., & Reilly, L. R. (2005). Journal of Investigative Dermatology, 129(12), 2751-2759. Hamblin, M. R. (2016). Jagdeo, J., Austin, E., Mamalis, A., Wong, C., Ho, D., & Siegel, D. M. (2018). However, the appropriate range of values of irradiance and fluence are not widely agreed upon. The beneficial effects of LLLT are governed by the ArndtSchultz law, which says that cells will respond differently to varying levels of irradiance (mW/cm2) or radiant exposure (J/cm2). Energy density is measured in joules per square centimeter (J/cm2) and is the amount of energy delivered into the tissue. Among clinical studies focused on skin rejuvenation, fluence values ranges from 1.2 J/cm2 to 126 J/cm2, with the median being 66 J/cm2. The 590nm wavelength really doesnt have evidence to support it, but at least there isnt evidence it is actually determinantal (like 390 or other blue wavelengths).
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